| 2020 | 3 | Angels | OF | David Calabrese | Maple | ON | Ontario Blue Jays/Junior National Team | $744,200 | $744,200 |
| 2010 | 10 | Astros | LHP | Evan Grills | Whitby | ON | Ontario Blue Jays/Junior National Team | $150,000 | $150,000 |
| 2014 | 6 | Astros | RHP | Brock Dykxhoorn | Goderich | ON | Central Arizona/ Ontario Nationals | $250,000 | $400,000 |
| 2016 | 5 | Astros | INF | Abraham Toro-Hernandez | Greenfield Park | QC | Seminole State/ ABC | $250,000 | $650,000 |
| 2017 | 12 | Astros | RF | Jonathan Lacroix | Montreal | QC | Seminole State/ ABC | $125,000 | $775,000 |
| 2018 | 6 | Astros | RHP | RJ Freure | Burlington | ON | Pitt/Junior National Team/Ontario Blue Jays | $348,800 | $1,123,800 |
| 1987 | 5 | Athletics | LHP | Kevin MacLeod | Sydney | NS | Toledo | $500,000 | $500,000 |
| 2019 | 12 | Athletics | INF | T.J. Schofield-Sam | Brampton | ON | Ontario Blue Jays/Junior National Team | $320,000 | $820,000 |
| 2021 | 4 | Athletics | OF | Denzel Clarke | Pickering | ON | Cal State Northridge Matadors/Toronto Mets/Junior National Team | $700,000 | $1,520,000 |
| 2023 | 1A | Athletics | INF | Myles Naylor | Mississauga | ON | Ontario Blue Jays/Junior National Team | $2,202,500 | $3,722,500 |
| 2024 | 6 | Athletics | RHP | Josiah Rome | Caledon | ON | Mississauga Tigers | $550,000 | $4,272,500 |
| 1995 | 24 | Blue Jays | LHP | Mark Curtis | St. Albert | AB | Penscaola/St. Albert Cardinals | $135,000 | $135,000 |
| 1996 | 3 | Blue Jays | RHP | Yan Lachapelle | Gatineau | QC | Academie du Baseball Canada | $185,000 | $320,000 |
| 2001 | 6 | Blue Jays | SS | Lee Delfino | Pickering | ON | East Carolina /Team Ontario/Junior National Team | $122,500 | $442,500 |
| 2006 | 7 | Blue Jays | OF | Jonathan Baksh | Mississauga | ON | Florida Tech/Ontario Blue Jays | $122,500 | $565,000 |
| 2007 | 1 | Blue Jays | RHP | Trystan Magnuson | Vancouver | BC | Louisville | $462,500 | $1,027,500 |
| 2008 | 16 | Blue Jays | OF | Mike Crouse | Port Moody | BC | North Shore Twins/Junior National Team | $150,000 | $1,177,500 |
| 2010 | 3 | Blue Jays | OF | Marcus Knecht | North York | ON | Connors State/ Ontario Blue Jays/Junior National Team | $250,000 | $1,427,500 |
| 2010 | 16 | Blue Jays | OF | Dalton Pompey | Mississauga | ON | Oakville Royals/Junior National Team | $150,000 | $1,577,500 |
| 2011 | 4 | Blue Jays | RHP | Tom Robson | Ladner | BC | Langley Blaze/Junior National Team | $325,000 | $1,902,500 |
| 2011 | 26 | Blue Jays | SS | Justin Atkinson | North Surrey | BC | Langley Blaze/Junior National Team | $100,000 | $2,002,500 |
| 2012 | 26 | Blue Jays | RHP | Nathan DeSouza | Milton | ON | Ontario Blue Jays/Junior National Team | $100,000 | $2,102,500 |
| 2015 | 10 | Blue Jays | C | Owen Spiwak | Mississauga | ON | Odessa/ Ontario Blue Jays/Junior National Team | $100,000 | $2,202,500 |
| 2019 | 3 | Blue Jays | OF | Dasan Brown | Oakville | ON | Ontario Blue Jays/Junior National Team | $800,000 | $3,002,500 |
| 2019 | 26 | Blue Jays | OF | Jean-Christophe Masson | Levis | QC | Academy Baseball Canada / Junior National Team | $297,500 | $3,300,000 |
| 2021 | 14 | Blue Jays | INF | Damiano Palmegiani | Surrey | BC | Southern Nevada/Vauxhall Jets/Junior National Team | $157,500 | $3,457,500 |
| 2023 | 5 | Blue Jays | LHP | Connor O'Halloran | Mississauga | ON | Michigan/Terriers | $337,500 | $3,795,000 |
| 2023 | 9 | Blue Jays | INF | Sam Shaw | Victoria | BC | Victoria Eagles | $285,000 | $4,080,000 |
| 2000 | 1 | Braves | INF | Scott Thorman | Cambridge | ON | Team Ontario/Junior National Team | $1,225,000 | $1,225,000 |
| 2001 | 3 | Braves | OF | Adam Stern | London | ON | Nebraska/Ontario Blue Jays/London Badgers | $348,000 | $1,573,000 |
| 2003 | 4 | Braves | 3B | Jamie Romak | London | ON | London Badgers / Junior National Team | $240,000 | $1,813,000 |
| 2015 | 1 | Braves | RHP | Michael Soroka | Calgary | AB | Calgary PBF Redbirds/Junior National Team | $1,974,700 | $3,787,700 |
| 2019 | 27 | Braves | RHP | Indigo Diaz | Langley | BC | Michigan State/North Shore Twins | $125,000 | $3,912,700 |
| 2019 | 28 | Braves | RHP | Ben Thompson | Auckland | NZ | Chandler-Gilbert College/Okotoks Dawgs | $100,000 | $4,012,700 |
| 2021 | 11 | Braves | LHP | Adam Shoemaker | Cambridge | ON | Great Lakes Canadians | $477,500 | $4,490,200 |
| 2022 | 4 | Braves | 1B | David McCabe | Courtice | ON | Ontario Blue Jays/UNC Charlotte | $476,500 | $4,966,700 |
| 2022 | 7 | Braves | RHP | Adam Maier | North Vancouver | BC | Oregon/North Shore Twins/Junior National Team | $1,200,000 | $6,166,700 |
| 2022 | 13 | Braves | RHP | Cedric DeGranpre | St-Simon | QC | ABC/Chipola | $237,500 | $6,404,200 |
| 2024 | 20 | Braves | OF | Eric Hartman | St. Albert | AB | Okotoks Dawgs/Junior National Team | $337,500 | $6,741,700 |
| 1993 | 2 | Brewers | SS | Danny Klassen | Leamington | ON | John Carroll HS, Port St. Lucie, Fla. | $180,000 | $180,000 |
| 2001 | 5 | Brewers | RHP | Judd Richardson | Caledon | ON | U of Miami Ohio | $185,000 | $365,000 |
| 2004 | 7 | Brewers | RHP | Craig Langille | Bedford | NS | Dartmouth Juniors | $107,000 | $472,000 |
| 2004 | 16 | Brewers | RHP | Alexandre Periard | St-Eustache | QC | Academie Baseball Canada / Junior National Team | $243,000 | $715,000 |
| 2008 | 16 | Brewers | RHP | Stosh Wawrzasek | Langley | BC | Langley Blaze/Junior National Team | $100,000 | $815,000 |
| 2008 | 1 | Brewers | C | Brett Lawrie | Langley | BC | Langley Blaze/Junior National Team | $1,700,000 | $2,515,000 |
| 2009 | 8 | Brewers | OF | Chad Stang | Surrey | BC | Midland/Junior National Team | $125,000 | $2,640,000 |
| 2010 | 7 | Brewers | RHP | Joel Pierce | Windsor | ON | Tecumseh Thunder / Junior National Team | $175,000 | $2,815,000 |
| 2011 | 8 | Brewers | C | Dustin Houle | Langley | BC | Langley Blaze/Junior National Team | $150,000 | $2,965,000 |
| 2012 | 7 | Brewers | LHP | David Otterman | Vancouver | BC | University of British Columbia | $141,700 | $3,106,700 |
| 2014 | 4 | Brewers | OF | Demi Orimoloye | Orleans | ON | Ottawa-Nepean Canadians/Junior National Team | $450,000 | $3,556,700 |
| 2021 | 1 | Brewers | INF | Tyler Black | Stouffville | ON | Wright State/ Toronto Mets | $2,200,000 | $5,756,700 |
| 2021 | 7 | Brewers | OF | Tristan Peters | Winkler | MB | Southern Illnois/Okotoks Dawgs/Pembina Valley Orioles | $147,500 | $5,904,200 |
| 2022 | 3 | Brewers | INF | Dylan O'Rae | Sarnia | ON | Great Lake Canadians/Junior National Team | $597,500 | $6,501,700 |
| 2001 | 28 | Cardinals | RHP | Blake Hawksworth | North Vancouver | BC | Bellevue (WA.) Community College | $1,475,000 | $1,475,000 |
| 2013 | 10 | Cardinals | SS | Malik Collymore | Mississauga | ON | Ontario Blue Jays / Junior National Team | $275,000 | $1,750,000 |
| 2018 | 15 | Cardinals | RHP | Michael Brettell | Fonthill | ON | Central Michigan/Great Lake Canadians/Junior National Team | $125,000 | $1,875,000 |
| 2009 | 5 | Cubs | SS | Wes Darvill | Langley | BC | Langley Blaze/Junior National Team | $144,200 | $144,200 |
| 2011 | 7 | Cubs | 1B | Trevor Gretzky | West Lake Village | CA | Oaks Christian High School | $375,000 | $519,200 |
| 2011 | 15 | Cubs | C | Justin Marra | Toronto | ON | Ontario Blue Jays / Junior National Team | $110,000 | $629,200 |
| 2013 | 2 | Cubs | LHP | Rob Zaztryzny | Edmonton | AB | Missouri | $1,100,000 | $1,729,200 |
| 2015 | 5 | Cubs | LHP | Ryan Kellogg | Whitby | ON | Arizona State/Butler Prospects/Junior National Team | $376,700 | $2,105,900 |
| 2017 | 15 | Cubs | INF | Jared Young | Prince George | BC | Old Dominion / Oakanagan A's | $100,000 | $2,205,900 |
| 2019 | 5 | Cubs | RHP | Josh Burgmann | Nanaimo | BC | Washington/Junior National Team/Vauxhall Academy | $225,000 | $2,430,900 |
| 2020 | 3 | Cubs | OF | Jordan Nwogu | Ottawa | ON | Michigan | $678,600 | $3,109,500 |
| 2021 | 18 | Cubs | RHP | Dominic Hambly | Victoria | BC | Victoria Mariners | $200,000 | $3,309,500 |
| 2016 | 2 | Diamondbacks | C | Andrew Yerzy | Toronto | ON | Toronto Mets/Junior National Team | $1,214,100 | $1,214,100 |
| 2016 | 4 | Diamondbacks | RHP | Curtis Taylor | Port Coquitlam | BC | University of British Columbia /Coquitlam Reds | $496,700 | $1,710,800 |
| 2016 | 11 | Diamondbacks | RHP | Jake Polanic | Langley | BC | Langley Blaze | $100,000 | $1,810,800 |
| 2022 | 13 | Diamondbacks | RHP | Eli Saul | Vancouver | BC | Sacramento State/Junior National Team/UBC Thunder | $120,000 | $1,930,800 |
| 2001 | 5 | Dodgers | RHP | Steve Nelson | Cole Harbour | NS | Dartmouth Mooseheads/Junior National Team | $165,000 | $165,000 |
| 2006 | 4 | Dodgers | INF | Kyle Orr | Victoria | BC | Victoria Mariners /Junior National Team | $435,000 | $600,000 |
| 2009 | 15 | Dodgers | 3B | Jeff Hunt | Cambridge | ON | Intercounty Terriers/Junior National Team | $150,000 | $750,000 |
| 2017 | 7 | Dodgers | RHP | Zach Pop | Brampton | ON | Kentucky / Ontario Blue Jays / Junior National Team | $147,500 | $897,500 |
| 2003 | 4 | Giants | RHP | Brooks McNiven | Vernon | BC | University of British Columbia | $105,000 | $105,000 |
| 2015 | 15 | Giants | C | Chris Shaw | Winnipeg | MB | Oklahoma/Okotoks Dawgs | $100,000 | $205,000 |
| 1997 | 2 | Guardians | RHP | Robbie Vael | Surrey | BC | Eastern Utah | $150,000 | $150,000 |
| 2005 | 3 | Guardians | OF | Nick Weglarz | Stevensville | ON | Team Ontario/Junior National Team | $435,000 | $585,000 |
| 2017 | 23 | Guardians | RHP | Jordan Scheltz | North York | ON | Central Florida | $100,000 | $685,000 |
| 2018 | 1 | Guardians | C | Noah Naylor | Mississauga | ON | Ontario Blue Jays/Junior National Team | $2,578,138 | $3,263,138 |
| 2022 | 15 | Guardians | LHP | Adam Tulloch | Toronto | ON | Arizona State | $125,000 | $3,388,138 |
| 2022 | 10 | Guardians | RHP | Jacob Zibin | Prince George | BC | Langley Blaze/TNXL/Junior National Team | $1,200,000 | $4,588,138 |
| 2023 | 10 | Guardians | LHP | Matt Wilkinson | White Rock | BC | Central Arizona/Okotoks Dawgs | $110,000 | $4,698,138 |
| 2024 | 12 | Guardians | RHP | Sean Heppner | Richmond | BC | University of British Columbia | $150,000 | $4,848,138 |
| 1994 | 32 | Mariners | LHP | Jordan Zimmerman | Caresland | AB | Blinn | $300,000 | $300,000 |
| 2001 | 5 | Mariners | 2B | John Cole | Kanata | ON | University of Nebraska/Ontario Blue Jays/Ottawa Nationals | $170,000 | $470,000 |
| 2004 | 11 | Mariners | OF | Mike Saunders | Victoria | BC | Victoria Mariners//Junior National Team | $237,500 | $707,500 |
| 2007 | 1 | Mariners | RHP | Phillippe Aumont | Gatineau | QC | ABC/Junior National Team | $1,900,000 | $2,607,500 |
| 2007 | 16 | Mariners | RHP | Colin Buckborough | Niagara Falls | ON | Bullett Proof Prospects/Junior National Team | $200,000 | $2,807,500 |
| 2013 | 3 | Mariners | OF | Tyler O'Neill | Maple Ridge | BC | Langley Blaze/Junior National Team | $650,000 | $3,457,500 |
| 2013 | 13 | Mariners | 3B | Lachlan Fontaine | North Vancouver | BC | North Shore Twins/Junior National Team | $100,000 | $3,557,500 |
| 2014 | 2 | Mariners | OF | Gareth Morgan | North York | ON | Ontario Blue Jays/Junior National Team | $2,000,000 | $5,557,500 |
| 2019 | 7 | Mariners | LHP | Adam Macko | Stony Plain | AB | Vauxhall Academy | $250,000 | $5,807,500 |
| 2005 | 7 | Marlins | RHP | Chris Leroux | Mississauaga | ON | Winthrop/Team Ontario/Junior National Team | $152,000 | $152,000 |
| 2015 | 1 | Marlins | 1B | Josh Naylor | Mississauga | ON | Ontario Blue Jays/Junior National Team | $2,250,000 | $2,402,000 |
| 2018 | 3 | Marlins | OF | Tristan Pompey | Mississauga | ON | Kentucky/Junior National Team/Toronto Mets | $645,000 | $3,047,000 |
| 2024 | 12 | Marlins | C | Connor Caskenette | Duncan | BC | Purdue | $100,000 | $3,147,000 |
| 2024 | 17 | Marlins | OF | Micah McDowell | Coldbrook | NS | Oregon State | $100,000 | $3,247,000 |
| 2003 | 48 | Mets | SS | Jonathan Malo | St-Roch-de-l'Achigan | QC | Northeastern Oklahoma A&M / Junior National Team/ABC | $125,000 | $125,000 |
| 2007 | 6 | Mets | RHP | Guillaume Leduc | Boucherville | QC | Academie Baseball Canada | $120,000 | $245,000 |
| 2021 | 2 | Mets | RHP | Calvin Ziegler | Heidelberg | ON | Great Lake Canadians/TNXL/Junior National Team | $910,000 | $1,155,000 |
| 2022 | 7 | Mets | RHP | Jonah Tong | Markham | ON | Toronto Mets/Frederick Keys MLB Draft League | $226,000 | $1,381,000 |
| 2022 | NDFA | Mets | RHP | Mathieu Voros | Anjou | QC | ABC/TNXL | $100,000 | $1,481,000 |
| 1993 | 2 | Nationals | RHP | Martin Mainville | Montreal | QC | Academie Baseball Canada | $115,000 | $115,000 |
| 2000 | 6 | Nationals | RHP | Shawn Hill | Georgetown | ON | Team Ontario/Etobicoke Rangers | $115,000 | $230,000 |
| 2017 | 13 | Nationals | OF | Eric Senior | Toronto | ON | Midland/ Toronto Mets | $100,000 | $330,000 |
| 2022 | 6 | Nationals | INF | Nate Ochoa | Burlington | ON | FieldHouse Pirates/Junior National Team | $375,000 | $705,000 |
| 1997 | 1 | Orioles | OF | Ntema Ndungidi | Montreal | QC | Academie Baseball Canada | $500,000 | $500,000 |
| 2002 | 1 | Orioles | LHP | Adam Loewen | Surrey | BC | Whalley Chiefs/Junior National Team | $3,200,000 | $3,700,000 |
| 2013 | 5 | Orioles | LHP | Travis Seabrooke | North Monaghan | ON | Terriers/Junior National Team | $291,800 | $3,991,800 |
| 2015 | 15 | Orioles | C | Chris Shaw | Winnipeg | MN | Oklahoma/Okotoks Dawgs | $100,000 | $4,091,800 |
| 2017 | 2 | Orioles | INF | Adam Hall | London | ON | Great Lake Canadians/Junior National Team | $1,300,000 | $5,391,800 |
| 1997 | 1 | Padres | SS | Kevin Nicholson | Surrey | BC | Stetson/ Junior National Team/Whalley Chiefs | $830,000 | $830,000 |
| 2002 | 20 | Padres | C | George Kottaras | Markham | ON | Connors State/ Ontario Blue Jays | $300,000 | $1,130,000 |
| 2010 | 4 | Padres | INF | Chris Bisson | Orleans | ON | Kentucky/Ottawa-Nepean Canadians/Junior National Team | $234,000 | $1,364,000 |
| 2016 | 1 | Padres | RHP | Cal Quantrill | Port Hope | ON | Stanford/Terriers/Junior National Team | $3,963,045 | $5,327,045 |
| 2018 | 14 | Padres | LHP | Erik Sabrowski | Edmonton | AB | Cloud County/Prospects Baseball Academy | $125,000 | $5,452,045 |
| 2019 | 4 | Padres | RHP | Matt Brash | Kingston | ON | Niagara/Kingston Thunder | $512,400 | $5,964,445 |
| 2020 | 2 | Padres | OF | Owen Caissie | Burlington | ON | FieldHouse Pirates/Junior National Team | $1,200,004 | $7,164,449 |
| 2009 | 6 | Phillies | RHP | Steven Inch | Edmonton | AB | Vauxhall Academy/Junior National Team | $300,000 | $300,000 |
| 2015 | 34 | Phillies | OF | Ben Pelletier | Varennes | QC | Patriotes Rive Sud/Score International | $135,000 | $435,000 |
| 2022 | NDFA | Phillies | C | Ryan Leitch | Whitby | QC | Marshall/Toronto Mets/Junior National Team | $125,000 | $560,000 |
| 2023 | 9 | Phillies | OF | Avery Owusu-Asiedu | Saskatoon | SK | Southern Illinois-Edwardsville | $150,000 | $710,000 |
| 2024 | 1 | Phillies | OF | Dante Nori | Toronto | ON | Northville HS (MI)/Canes National | $2,500,000 | $3,210,000 |
| 2007 | 35 | Pirates | RHP | Tom Boleska | Burlington | ON | High Point/Team Ontario/Junior National Team | $100,000 | $100,000 |
| 2010 | 1 | Pirates | RHP | Jameson Taillon | The Woodlands | TX | The Woodlands HS | $6,500,000 | $6,600,000 |
| 2012 | 6 | Pirates | 3B | Eric Wood | Pickering | ON | Blinn/Ontario Blue Jays | $100,000 | $6,700,000 |
| 2016 | 33 | Pirates | RHP | Austin Shields | Dundas | ON | Great Lake Canadians / Junior National Team | $205,000 | $6,905,000 |
| 2020 | 5 | Pirates | RHP | Logan Hofmann | Muenster | SK | Northwestern State University/Team Sask | $125,000 | $7,030,000 |
| 2023 | NDFA | Pirates | RHP | Noah Takacs | Victoria | BC | Sacramento State | $150,000 | $7,180,000 |
| 1995 | 3 | Rangers | RHP | Ryan Dempster | Gibsons | BC | North Shore Twins/Junior National Team | $200,000 | $200,000 |
| 2004 | 5 | Rangers | C | Mike Nickeas | Vancouver | BC | Georgia Tech | $200,000 | $400,000 |
| 2010 | 1 | Rangers | C | Kellin Deglan | Langley | BC | Langley Blaze/Junior National Team | $1,000,000 | $1,400,000 |
| 2010 | 32 | Rangers | RHP | Steve McKinnon | Duncan | BC | Nanaimo Pirates/Junior National Team | $150,000 | $1,550,000 |
| 2016 | 4 | Rangers | INF | Charles Leblanc | Laval | QC | Pitt/Junior National team/ABC | $415,000 | $1,965,000 |
| 2021 | 5 | Rangers | LHP | Mitch Bratt | Newmarket | ON | Toronto Mets/Georgia Premier/Junior National Team | $850,000 | $2,815,000 |
| 2021 | 13 | Rangers | LHP | Thomas Ireland | Regina | SK | Polk State/Inside Pitch Prospects/Martin Academy/Regina Buffalos | $125,000 | $2,940,000 |
| 2021 | 15 | Rangers | RHP | Evan Elliott | Toronto | ON | Prairie Baseball Academy/Terriers/Junior National Team | $125,000 | $3,065,000 |
| 2008 | 11 | Rays | RHP | Brad Furdal | Ancaster | ON | Inter County Terriers/Junior National Team | $140,000 | $140,000 |
| 2023 | 18 | Rays | LHP | Jérémy Pilon | Salaberry-De-Valleyfield | QC | Academie Baseball Canada, Junior National Team | $172,500 | $312,500 |
| 2024 | 2 | Rays | INF | Émilien Pitre | Repentigny | QC | Kentucky | $1,520,000 | $1,832,500 |
| 2024 | 3 | Rays | C | Nathan Flewelling | Innisfail | AB | Red Deer Braves/Junior National Team | $774,000 | $2,606,500 |
| 2024 | 12 | Rays | INF | Jack Lines | Okotoks | AB | TXNL/Okotoks Dawgs | $397,500 | $3,004,000 |
| 1996 | 2 | Red Sox | RHP | Chris Reitsma | Calgary | AB | Calgary Rockies/Junior National Team | $425,000 | $425,000 |
| 2018 | 4 | Red Sox | C-1B | Kole Cottam | Memphis | TN | Kentucky | $375,000 | $800,000 |
| 2022 | 15 | Red Sox | LHP | Nathan Landry | Victoriaville | QC | Missouri/ABC | $112,500 | $912,500 |
| 2023 | 4 | Red Sox | RHP | Matt Duffy | Burlington | ON | Canisius/Greaat Lake Canadians | $350,000 | $1,262,500 |
| 2002 | 2 | Reds | INF | Joey Votto | Etobicoke | ON | Etobicoke Rangers | $600,000 | $600,000 |
| 2004 | 7 | Reds | LHP | Philippe-Alexandre Valiquette | St. Laurent | QC | Academie Baseball Canadaé /Junior National Team | $300,000 | $900,000 |
| 2005 | 5 | Reds | RHP | James Avery | Maple Creek | SK | Niagara/Okotoks Dawgs | $170,000 | $1,070,000 |
| 2007 | 1 | Reds | RHP | Kyle Lotzkar | Tsawwassen | BC | Langley Blaze/Junior National Team | $594,000 | $1,664,000 |
| 2007 | 6 | Reds | RHP | Evan Hildebrandt | Abbotsford | BC | Abbotsford Cardinals/Junior National Team | $200,000 | $1,864,000 |
| 2008 | 16 | Reds | OF | Carter Morrison | Langley | BC | Langley Blaze/Junior National Team | $132,000 | $1,996,000 |
| 2010 | 34 | Reds | SS | Brandon Dailey | Brantford | ON | Ontario Terriers/Junior National Team | $100,000 | $2,096,000 |
| 2011 | 11 | Reds | RHP | Vaughn Covington | Vancouver | BC | Vancouver Cannons/Junior National Team | $150,000 | $2,246,000 |
| 2013 | 20 | Reds | C | Morgan Lofstrom | Kelowna | BC | Okanagan Athletics/Junior National Team | $100,000 | $2,346,000 |
| 2015 | 4 | Reds | CF | Miles Gordon | Oakville | ON | Great Lake Canadians/Junior National Team | $500,000 | $2,846,000 |
| 2015 | 17 | Reds | 2B | J.D. Salmon-Willams | Brampton | ON | Ontario Blue Jays/Junior National Team | $100,000 | $2,946,000 |
| 2015 | 18 | Reds | LHP | Isaac Annesty | Guelph | ON | Ontario Blue Jays/Junior National Team | $200,000 | $3,146,000 |
| 2015 | 22 | Reds | RHP | Darren Shred | Brampton | ON | Ontario Blue Jays/Junior National Team | $100,000 | $3,246,000 |
| 2015 | 27 | Reds | INF | Alejo López | Mexico | Mex | Greenway HS, Phoenix/Okotoks Dawgs | $150,000 | $3,396,000 |
| 2016 | 24 | Reds | 1B | Bruce Yari | Waterloo | ON | University of British Columbia | $125,000 | $3,521,000 |
| 2002 | 1 | Rockies | LHP | Jeff Francis | North Delta | BC | University of British Columbia/Junior National Team/North Delta Blue Jays | $1,850,000 | $1,850,000 |
| 2007 | 3 | Rockies | C | Lars Davis | Grande Prairie | AB | Illinois | $337,000 | $2,187,000 |
| 2007 | 4 | Royals | RHP | Mitch Hodge | Vancouver | BC | White Rock Titons/Junior National Team | $225,000 | $225,000 |
| 2010 | 4 | Royals | LHP | Kevin Chapman | Coral Springs | FL | University of Florida | $250,000 | $475,000 |
| 2021 | 5 | Royals | RHP | Eric Cerantola | Oakville | ON | Mississippi State/Great Lakes Canadians/Junior National Team | $500,000 | $975,000 |
| 2022 | UFA | Royals | LHP | Jordan Woods | Oakville | ON | Terriers/Junior National Team | $125,000 | $1,100,000 |
| 2024 | 4 | Royals | RHP | Louis-Philippe Langevin | Quebec | QC | Louisiana-Lafayette | $597,500 | $1,697,500 |
| 2005 | 3 | Tigers | C | Chris Robinson | Dorchester | ON | Illinois/Junior National Team/London Badgers | $422,500 | $422,500 |
| 2016 | 8 | Tigers | OF | Jacob Robson | Windsor | ON | Mississippi State /Ontario Blue Jays/Junior National Team | $181,600 | $604,100 |
| 2016 | 9 | Tigers | INF | Daniel Pinero | Toronto | ON | Virginia/Ontario Blue Jays/Junior National Team | $169,600 | $773,700 |
| 2020 | 3 | Tigers | INF | Trei Cruz | Houston | TX | Rice | $900,000 | $1,673,700 |
| 2021 | 8 | Tigers | RHP | Jordan Marks | Bright's Grove | ON | South Carolina-Upstate/Great Lakes Canadians | $150,000 | $1,823,700 |
| 2023 | 15 | Tigers | C | Brady Cerkownyk | Etobicoke | ON | Connors State | $397,500 | $2,221,200 |
| 1999 | 3 | Twins | C | Justin Morneau | New Westminister | BC | North Delta Blue Jays/Junior National Team | $295,000 | $295,000 |
| 2002 | 2 | Twins | RHP | Jesse Crain | Toronto | ON | Houston | $650,000 | $945,000 |
| 2003 | 40 | Twins | RHP | Adam Hawes | Victoria Harbour | ON | Connors State/Ontario Blue Jays | $118,000 | $1,063,000 |
| 2006 | 7 | Twins | 1B | Jonathan Walterbury | Whitby | ON | Ontario Blue Jays/Junior National Team | $128,500 | $1,191,500 |
| 2016 | 5 | Twins | RHP | Jordan Balazovic | Mississauga | ON | Ontario Blue Jays/Junior National Team | $515,000 | $1,706,500 |
| 2017 | 2 | Twins | RHP | Landon Leach | Pickering | ON | Toronto Mets/Junior National Team | $1,400,000 | $3,106,500 |
| 2018 | 25 | Twins | C | LaRon Smith | Spruce Grove | AB | Okotoks Dawgs/Junior National Team | $125,000 | $3,231,500 |
| 2019 | 18 | Twins | INF | Edouard Julien | Quebec City | QC | Auburn/Junior National Team/ABC | $493,000 | $3,724,500 |
| 2021 | 5 | Twins | LHP | Christian MacLeod | Huntsville | AL | Mississippi State | $500,000 | $4,224,500 |
| 1997 | 1 | White Sox | RHP | Aaron Myette | Surrey | BC | Central Arizona/Whalley/Junior National Team | $375,000 | $375,000 |
| 2017 | 22 | White Sox | RHP | Byran Saucedo | Toronto | ON | Davenport/Junior National Team/Ontario Blue Jays | $100,000 | $475,000 |
| 2003 | 5 | Yankees | RHP | Cory Stuart | White Rock | BC | University of British Columbia | $170,000 | $170,000 |
| 2010 | 16 | Yankees | LHP | Evan Rutckyj | Windsor | ON | Windsor Selects/Detroit Jet Box/Junior National Team | $500,000 | $670,000 |
| 2012 | 15 | Yankees | RHP | Dayton Dawe | London | ON | Terriers /Junior National Team | $100,000 | $770,000 |
| 2015 | 2 | Yankees | LHP | Jeff Degano | Surrey | BC | Indiana State | $650,000 | $1,420,000 |
| 2019 | 3 | Yankees | OF | Jacob Sanford | Cole Harbour | NS | Western Kentucky | $597,500 | $2,017,500 |
| 2023 | 3 | Yankees | LHP | Kyle Carr | Sydney | NS | Palomar | $692,000 | $2,709,500 |
